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12 Dec 2025

The Science Behind Nitralis

Why does it work so well ?

A question we've received a lot since introducing Nitralis® is:

Why does it work so well compared to other 'nitric oxide (NO) boosters' on the market?

Here's why Nitralis® is the best NO booster there is:


Nitrate-nitrite vs Arginine

The active ingredient in many so-called NO boosters is arginine, an amino acid that is used by the body to make nitric oxide via something called the arginine-NO pathway.

As we get older, our natural levels of NO drop and so does the efficiency of the arginine-NO pathway.

This means that giving an ageing body more arginine will not produce more NO - it's like pouring the wrong fuel into a broken engine and expecting it to work.

Nitralis® bypasses this by using a different pathway - the nitrate-nitrite-NO pathway - which remains efficient as we age.


Nitric oxide's short lifespan

Another common issue with nitric oxide boosters is that, even if they manage to produce nitric oxide, its effects are short lived as the molecule degrades quickly.

Nitralis® stabilises nitric oxide and keeps it bioactive for longer,

giving your body the maximum long-term benefits.


Commitment to research.

The final key reason why Nitralis® outperforms other so-called NO boosters is that

DoNotAge would not release an ingredient without proving it could deliver results.

They ran a clinical trial earlier this year that showed Nitralis® increased

participants' levels of nitric oxide by over 200% after just 30 days.


That's the difference.

No other company has taken as many steps to ensure the quality of their ingredient.

While anyone can talk about commitment to purity and effectiveness, we can demonstrate it.

We know Nitralis® uses quality ingredients because DoNotAge developed it.

We know it works because they ran the human clinical trial to prove it!

That's what you get with DoNotAge Nitralis®

Real science. Real results. Never anything less.

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